Selected Publications:

1. Block to the production of full-length B19 virus transcripts by internal polyadenylation is overcome by replication of the viral genome.
Wuxiang Guan, Fang Cheng, Yoko Yoto, Steve S. Kleiboeker, Susan Wong, Ning Zhi, David Pintel and Jianming Qiu
J Virol. 2008 Oct;82(20):9951-63.

2. Molecular characterization of infectious clones of the minute virus of canines reveals unique features of Bocaviruses.
Yuning Sun, Aaron Yun Chen, Fang Cheng, Wuxiang Guan, F. Brent Johnson, and Jianming Qiu
J. Virol. 2009 Apr;83(8):3956-67.

3. The genome of human parvovirus b19 can replicate in nonpermissive cells with the help of adenovirus genes and produces infectious virus.
Wuxiang Guan, Susan Wong, Ning Zhi and Jianming Qiu
J. Virol. 2009 Sep;83(18):9541-53.

4. Molecular characterization of human parvovirus B19 genotypes 2 and 3.
Zhaojun Chen, Wuxiang Guan, Fang Cheng, Aaron Yun Chen and Jianming Qiu
Virology. 2009 Nov 25;394(2):276-85.

5. The small 11kDa non-structural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells.
Chen AY, Zhang EY, Guan W, Cheng F, Kleiboeker S, Yankee TM and Jianming Qiu
Blood. 2010 Feb 4; 115(5):1070-1080.
Editorial Comment: Getting Personal with B19 Parvovirus.

6. The capsid proteins of Aleutian mink disease virus (AMDV) activate caspases and are specifically cleaved during infection.
Cheng F, Chen AY, Best SM, Bloom ME, Pintel D and Jianming Qiu
J Virol. 2010 Mar;84(6):2687-96. PMID: 20042496.

7. Bocavirus infection induces a mitochondrion-mediated apoptosis and cell cycle arrest at G2/M-phase.
Aaron Yun Chen, Yong Luo, Fang Cheng, Yuning Sun, and Jianming Qiu
J Virol. 2010 Jun;84(11):5615-26.

8. Characterization of the gene expression profile of human bocavirus.
Aaron Yun Chen, Fang Cheng, Sai Lou, Yong Luo, Zhengwen Liu, Eric Delwart, David Pintel, Jianming Qiu,
Virology 403 (2010) 145-154.

9.Role of Erythropoietin Receptor Signaling in Parvovirus B19 Replication in Human Erythroid Progenitor Cells.
Aaron Yun Chen, Wuxiang Guan, Sai Lou, Zhengwen Liu, Steve Kleiboeker and Jianming Qiu
J. Virol. 2010 Dec; 84(23):12385-96

10.Chipmunk Parvovirus Is Distinct from Members in the Genus Erythrovirus of the Family Parvoviridae.
Zhaojun Chen, Aaron Yun Chen, Fang Cheng, and Jianming Qiu
PLoS ONE, December 2010, 5(2):e15113

11.Parvovirus Infection-Induced Cell Death and Cell Cycle Arrest (Review).
Aaron Yun Chen and Jianming Qiu
Future Virology, November 2010, 5(6):731-743.

12.Bocavirus Infection Induces a DNA Damage Response That Facilitates Viral DNA Replication and Mediates Cell Death.
Yong Luo, Aaron Yun Chen, and Jianming Qiu
J. Virol. 2011 Jan;85(1):133-45.

13.Inclusion of the Central Exon of Parvovirus B19 Precursor mRNA is Determined by Multiple Splicing Enhancers both in the Exon and the Downstream Intron.
Wuxiang Guan, Fang Cheng, Qinfeng Huang, Steve Kleiboeker, and Jianming Qiu
J. Virol.2011 Mar;85(5):2463-8.

14.Internal Polyadenylation of the Parvovirus B19 Precursor mRNA is Regulated by Alternative Splicing.
Wuxiang Guan, Qinfeng Huang, Fang Cheng, and Jianming Qiu
J. Biol. Chem. 2011 Jul 15;286(28):24793-805.

15.Parvovirus B19 infection of primary human erythroid progenitor cells triggers ATR-Chk1 signaling, which promotes B19 replication.
Yong Luo, Sai Lou, Xuefeng Deng, Zhengwen Liu, Yi Li, Steve Kleiboeker and Jianming Qiu
J. Virol. 2011, 85(16): 8046-8055.

16.Productive Parvovirus B19 Infection of Primary Human Erythroid Progenitor Cells at Hypoxia is Regulated by STAT5A and MEK Signaling but not HIFa.
Aaron Yun Chen, Steve Kleiboeker and Jianming Qiu
PLoS Pathogens. 2011 Jun;7(6):e1002088.

17.Molecular characterization of the newly identified human parvovirus 4 in the family Parvoviridae.
Sai Lou, Baoyan Xu, Qinfeng Huang, Ning Zhi, Fang Cheng, Susan Wong, Kevin Brown, Eric Delwart, Zhengwen Liu and Jianming Qiu
Virology. 2012 Jan 5; 422(1):59-69.

18.Genome Features of the Human Bocaviruses (Review).
Oliver Schildgen, Jianming Qiu and Maria Soderlund-Venemo
Future Virology. 2012; 7(1): 31-39.

19.Internal Polyadenylation of Parvoviral Precursor mRNA Limits Progeny Virus Production.
Qinfeng Huang, Xuefeng Deng, Sonja M Best, Marshall E Bloom, Yi Li and Jianming Qiu
Virology. 2012, 426(2):167-77.

20.Human Parvovirus B19 DNA Replication Induces a DNA Damage Response That is Dispensable for Cell Cycle Arrest at G2/M Phase.
Sai Lou, Yong Luo, Fang Cheng, Qinfeng Huang, Weiran Shen, Steve Kleiboeker, John F. Tisdale, Zhengwen Liu, Jianming Qiu
Journal of Virology, 2012, 86(19):10748-58.

21.Establishment of a Reverse Genetics System for the Study of Human Bocavirus and Evidence of Cytopathogenesis in Polarized Human Airway Epithelia.
Qinfeng Huang, Xuefeng Deng, Ziying Yan, Fang Cheng, Yong Luo, Weiran Shen, Diana C.M. Lei-Butters, Aaron Yun Chen, Yi Li, Liang Tang, Maria Soderlund-Venermo, John F. Engelhardt and Jianming Qiu
PLoS Pathogens, 2012, 8(8):e1002899.

22.In vitro modeling of human bocavirus 1 infection of polarized primary human airway epithelia.
Xuefeng Deng, Ziying Yan, Yong Luo, Jian Xu, Fang Cheng, Yi Li, John F. Engelhardt, Jianming Qiu
Journal of Virology. 2013, 87(7):4097-4102.

23.Characterization of the Nonstructural Proteins of the Bocavirus Minute Virus of Canines.
Loretta Sukhu, Olufemi Fasina, Lisa Burger, Ayushi Rai, Jianming Qiu and David J. Pintel
Journal of Virology. 2013, 87(2): 1098–1104.

24.SMC1-mediated intra-S phase arrest facilitates Bocavirus DNA replication.
Yong Luo, Xuefeng Deng, Fang Cheng, Yi Li, Jianming Qiu
Journal of Virology. 2013, 87(7):4017-4032.

25.Parvovirus-induced DNA damage response (review).
Yong Luo and Jianming Qiu
Future Virology. 2013, 8:245-257.

26.A Novel Chimeric Adenoassociated Virus 2/Human Bocavirus 1 Parvovirus Vector Efficiently Transduces Human Airway Epithelia.
Ziying Yan, Nicholas W Keiser, Yi Song, Xuefeng Deng, Fang Cheng, Jianming Qiu and John F Engelhardt
Mol Ther. 2013 Jul 30. doi: 10.1038/mt.2013.92.

27.Structure of the NS1 protein N-terminal origin-recognition/nickase domain from the emerging human bocavirus.
Sunil Kumar Tewary, Haiyan Zhao, Weiran Shen, Jianming Qiu and Liang Tang
Journal of Virology. 2013, 87:11487-11493.

28.Human parvovirus B19 infection causes cell cycle arrest of human erythroid progenitors at late S phase that favors viral DNA replication.
Yong Luo, Steve Kleiboeker, Xuefeng Deng and Jianming Qiu
Journal of Virology. 2013, 87:12766-75.

29.Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively.
Xuefeng Deng, Yi Li and Jianming Qiu
Journal of Virological Methods. 2014, 195: 112–119.

30.Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection.
Qinfeng Huang, Yong Luo, Fang Cheng Sonja M. Best Marshall E. Bloom and Jianming Qiu
Virology. 2014, 452-453: 23–31.

31.Human parvovirus B19: a mechanistic overview of infection and DNA replication.
Yong Luo and Jianming Qiu
Future Virol. (2015) 10(2), 155–167.

32.Identification and Functional Analysis of Novel Non-structural Proteins of Human Bocavirus 1.
Weiran Shen, Xuefeng Deng, Wei Zou, Fang Cheng, John F Engelhardt, Ziying Yan, and Jianming Qiu
J. Virol. 2015, 89(19):10097-10109.

33.Replication of an Autonomous Human Parvovirus in Non-dividing Human Airway Epithelium Is Facilitated through the DNA Damage and Repair Pathways.
Xuefeng Deng, Ziying Yan, Fang Cheng, John F. Engelhardt, and Jianming Qiu
PLOS Pathogens.2016, 12(1):e1005399

34.Nonstructural Protein NP1 of Human Bocavirus 1 Plays a Critical Role in the Expression of Viral Capsid Proteins.
Wei Zou, Fang Cheng, Weiran Shen,John F. Engelhardt, Ziying Yan, and Jianming Qiu.
J. Virol. 2016, 90(9):4658-4669.

35. Analysis of the Cis and Trans Requirements for DNA Replication at the Right End Hairpin of the Human Bocavirus 1 Genome.
Weiran Shen, Xuefeng Deng, Wei Zou, John F. Engelhardt, Ziying Yan, and Jianming Qiu
J. Virol. 2016, 90(17):7761-7777.

36. The DNA damage signaling is required for replication of the HBoV1 DNA in dividing HEK293 cells.
Xuefeng Deng, Peng Xu, Wei Zou, Weiran Shen, Jianxin Peng, Kaiyu Liu, John F. Engelhardt, Ziying Yan, and Jianming Qiu.
J. Virol. 2017, 91(1):e01831-16.

37. Human Parvoviruses.
Jianming Qiu, Maria Söderlund-Venermo, and Neal S. Young.
Clinical Microbiology Review, 2017, 30(1):41-113.

38. Parvovirus Expresses a Small Noncoding RNA That Plays an Essential Role in Virus Replication.
Zekun Wang, Weiran Shen, Fang Cheng, Xuefeng Deng, John F. Engelhardt, Ziying Yan, and Jianming Qiu.
J. Virol, 2017, 91(8): e02375-16.

39. Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway.
Peng Xu, Zhe Zhou, Min Xiong, Wei Zou, Xuefeng Deng, Safder S Ganaie, Steve Kleiboeker, Jianxin Peng, Kaiyu Liu, Shengqi Wang, Shui Qing Ye, Jianming Qiu.
PLoS Pathogens. 2017, 13(3)e1006266.

40. Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex.
Safder S. Ganaie, Wei Zou, Peng Xu, Xuefeng Deng, Steve Kleiboeker, and Jianming Qiu.
PLoS Pathogens. 2017, 13(5):e1006370.

41. Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication.
Zekun Wang, Xuefeng Deng, Wei Zou, John F. Engelhardt, Ziying Yan, and Jianming Qiua.
J. Virol. 2017, 91(18):e00710-17.

42. Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor.
Sirika Pillay*, Wei Zou*, Fang Cheng, Andreas S. Puschnik, Nancy L. Meyer, Safder S. Ganaie, Xuefeng Deng, Jonathan E. Wosen, Omar Davulcu, Ziying Yan, John F. Engelhardt, Kevin E. Brown, Michael S. Chapman, Jan E. Carettea*, and Jianming Qiu*.
J. Virol. 2017, 91(18):e00391-17 (*Equal contribution).

43. Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death via Inhibiting Apoptosis.
Xuefeng Deng, Wei Zou, Min Xiong, Zekun Wang, John F. Engelhardt, Shui Qing Ye, Ziying Yan, and Jianming Qiu.
J. Virol. 2017, 91(24). pii: e01533-17.

44. Human Parvovirus B19 Utilizes Cellular DNA Replication Machinery for Viral DNA Replication.
Wei Zou, Zekun Wang, Min Xiong, Aaron Yun Chen, Peng Xu, Safder S. Ganaie, Yomna Badawi, Steve Kleiboeker, Hiroshi Nishimune, Shui Qing Ye, and Jianming Qiu.
J. Virol. 2018, 92 (5), e01881-12017.

45. An alternate route for adeno-associated virus (AAV) entry independent of AAV receptor
Amanda M Dudek, Sirika Pillay, Andreas S Puschnik, Claude M Nagamine, Fang Cheng, Jianming Qiu, Jan E Carette, Luk H Vandenberghe.
J. Virol. 2018, 92(7), e02213-17.

46. RNA binding protein RBM38 regulates expression of the 11-kilodalton protein of parvovirus B19, which facilitates viral DNA replication.
SS Ganaie, AY Chen, C Huang, P Xu, S Kleiboeker, A Du, J Qiu.
Journal of virology, 2018, 92(8), e02050-17.

47. Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes.
Z Wang, F Cheng, JF Engelhardt, Z Yan, J Qiu.
Molecular Therapy-Methods & Clinical Development, 2018(11), 40-51.

48. The 11-kilodalton nonstructural protein of human parvovirus B19 facilitates viral DNA replication by interacting with grb2 through its proline-rich motifs.
Peng Xu, Aaron Yun Chen, Safder S Ganaie, Fang Cheng, Weiran Shen, Xiaomei Wang, Steve Kleiboeker, Yi Li, Jianming Qiu.
Journal of virology, 2019, 93(1), e01464-18.

49. Endonuclease activity inhibition of the NS1 protein of parvovirus B19 as a novel target for antiviral drug development
Peng Xu, Safder S Ganaie, Xiaomei Wang, Zekun Wang, Steve Kleiboeker, Nancy C Horton, Richard F Heier, Marvin J Meyers, John E Tavis, Jianming Qiu.
Antimicrobial Agents and Chemotherapy, 2019, 63(3), e01879-18.

Search Publications on PubMed:
Qiu bibliography

Qiu Lab
Department of Microbiology
University of Kansas Medical Center